Metagenics
Metagenics Magnesium Glycinate - Pure, Flexible-Dose Bisglycinate for Sleep and Stress Support (120 Tablets)
The budget-friendly, flexible-dose glycinate in our lineup. 100 mg of pure magnesium bisglycinate per tablet, take one or two depending on how much you need.
- 100 mg of pure magnesium bisglycinate per tablet. No oxide blend, no buffered complex, just the well-tolerated chelate on its own.
- The reason we actually carry this one. When our own team tested it, we noticed a felt effect within 30 to 60 minutes, faster than we typically expect from magnesium. That's our observation, not a brand claim, and it's the real reason this product earned a spot on our shelf over other glycinate options.
- Dosing you can actually adjust. Take 1 tablet for a lighter daily amount or 2 for a fuller serving, your call, not a fixed multi-capsule serving.
- Third-party tested, vegetarian, gluten-free, dairy-free, Non-GMO. Verified independently, not just stated on the label.
- Gentle on the stomach. Bisglycinate's general reputation for being one of the easier magnesium forms to tolerate, with no oxide component to work around.
- A practitioner-channel brand at a genuinely accessible price. Metagenics has a long reputation among healthcare providers, priced well below some of the other practitioner brands we carry.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
This is the budget option in our magnesium lineup, and the honest reason to reach for it isn’t that it’s better than what we already carry, it’s that it’s simpler and cheaper, with dosing you control directly. One tablet is 100 mg of straightforward magnesium bisglycinate, no oxide blend, no brain-targeted threonate story, just the mineral in one of its more tolerable forms. Take one tablet for a light daily dose, or two if you want closer to what most glycinate research actually uses.
Two claims worth being precise about, since they come from different places. “4x better absorption” is the brand’s own marketing claim; it doesn’t specify what it’s being compared against in the material we have, so we’re passing it along as Metagenics’ positioning, not something we’ve independently verified ourselves. “Starts working in 30 to 60 minutes” is different: that one is ours. It’s our own team’s observation from testing this product firsthand, not a line from the brand’s packaging, and it’s actually the specific reason this earned a spot in our shop over other glycinate options we looked at, a faster subjective effect than we typically expect from magnesium. We’d rather tell you plainly which claim is ours and which is the brand’s than blur the two together.
One more number worth knowing: the Supplement Facts panel lists the serving size as 1 tablet (100 mg, 24% DV), while the brand’s own “60-day supply” claim only works out if you’re taking 2 tablets a day (200 mg total). That’s not a contradiction, just two different ways of describing the same bottle, but we’d rather show you the math than let you assume “120 tablets” automatically means a 4-month supply if you’re following the brand’s own suggested use.
Product Details
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What is in the tablet, and why
Magnesium bisglycinate, 100 mg per tablet, with a short list of standard tableting ingredients: microcrystalline cellulose, vegetable-derived stearic acid, croscarmellose sodium, and silica. No oxide, no other minerals, no proprietary blend name standing in for a real ingredient list.
On the absorption and onset claims, honestly
Bisglycinate has a solid general reputation for better absorption and gentler digestion than cheaper forms like magnesium oxide, and that reputation is well-supported in the broader magnesium literature. The specific "4x better absorption" figure is the brand's own marketing claim; it doesn't name a comparison point in the material available to us, so we're passing it along as Metagenics' positioning rather than something we've verified ourselves. The "30 to 60 minutes" onset claim is different, and worth being clear about: that one is ours, from our own team's use of this specific product, not a line from the brand's marketing. We're comfortable standing behind it as our own honest observation, though it's still one team's experience rather than a clinical measurement, and individual response to any magnesium product varies.
Dosing flexibility, and what it actually means for you
Because the tablet is a single, modest 100 mg dose, you have more granular control here than with a fixed multi-capsule serving. One tablet is a light, maintenance-level dose. Two tablets (200 mg) lines up more closely with doses used in general magnesium glycinate research and is the brand's own suggested full serving.
Magnesium's broader role, briefly
Magnesium supports nerve signaling, muscle relaxation, bone density, cardiovascular function, and the pathways involved in melatonin regulation and sleep, the same broad list that shows up across every magnesium form we carry. None of that is specific to this product; it's the general case for keeping magnesium intake adequate, which a meaningful share of adults don't manage through diet alone.
How this compares to our other glycinate option
| Metagenics Magnesium Glycinate | DFH Magnesium Glycinate Complex | |
|---|---|---|
| Form | Pure magnesium bisglycinate | TRAACS® bisglycinate chelate, buffered with magnesium oxide |
| Magnesium per serving | 100 mg (1 tablet) or 200 mg (2 tablets) | 300 mg (2 capsules, fixed) |
| Format | Tablet | Capsule |
| Dosing flexibility | Adjustable, 1 or 2 tablets | Fixed serving |
| One-time price | $33.75 | $64.99 |
| Cost per mg of magnesium | Slightly higher per mg | Slightly lower per mg |
Worth being upfront about: despite the lower sticker price, this product actually costs a bit more per milligram of elemental magnesium than our buffered complex option, since that one delivers a higher dose per dollar. Where this one wins is total flexibility and a lower total spend if you only want a modest 100 to 200 mg daily rather than a fixed 300 mg dose.
Who it tends to suit
- Anyone who wants to try glycinate-form magnesium without committing to a higher-dose, higher-priced product first.
- People who prefer adjusting their own dose rather than taking a fixed multi-capsule serving.
- Anyone specifically looking for a simple, single-ingredient tablet with no oxide component.
Who it is probably not for
- Anyone who wants the highest elemental dose per serving without taking multiple tablets; our buffered complex delivers more magnesium in a single 2-capsule serving.
- Anyone specifically chasing the brain-targeted threonate story; this is a general-purpose glycinate, not a cognitive-specific product.
- Anyone with kidney disease without medical guidance, since magnesium clearance depends on healthy kidney function.
How To Use
Start with 1 tablet and decide from there whether you want 2. There's no need to default straight to the brand's full suggested serving if you're not sure how you'll respond; magnesium's digestive effects are dose-dependent, and starting lower is a reasonable way to find your own tolerance.
An evening dose is a sensible default if sleep or stress relief is your main goal. Magnesium's role in the pathways tied to sleep makes this a logical time to take it, though there's no strict requirement to do so for the general muscle, bone, or nerve-related roles.
Give the deeper effects real time. The faster subjective effect our own team noticed within 30 to 60 minutes is a different thing from magnesium status normalizing throughout the body, which research on magnesium generally suggests takes closer to a few weeks of consistent daily use. Don't judge the ongoing, foundational benefits by how quickly you feel something after the first dose.
How to stack it
- Fits cleanly alongside our caffeine and theanine capsules, a choline source, or an omega-3, no mechanism overlap.
- If you're also taking one of our other magnesium products, add up total elemental magnesium rather than stacking full doses of more than one.
- No cycling required. This is meant to be a steady, ongoing daily foundation.
What to avoid
- Taking it within 2 hours of certain antibiotics (tetracycline or quinolone-class) or bisphosphonate medications, since magnesium can interfere with their absorption.
- Assuming 2 tablets is mandatory. The label's actual serving size is 1 tablet; 2 is the brand's suggested fuller dose, not a requirement.
Third Party Lab Testing
- Third-party tested, verified independently rather than taken on the brand's word alone.
- Non-GMO verified, gluten-free, and dairy-free, as stated on the label.
- Free from artificial colors, flavors, and unnecessary additives, per the brand's own claims.
- Metagenics is a longstanding practitioner-channel brand, commonly recommended by healthcare providers. We're presenting that as context on the brand's positioning rather than a claim we've independently ranked or verified.
As with any supplement, the strongest form of proof is a batch-specific Certificate of Analysis tied to the lot number on your bottle. If verifying a specific batch matters to you, note the lot number and request the COA directly from the manufacturer.
Ingredients
Supplement Facts - Serving Size: 1 Tablet - Servings Per Container: 120
| Per 1 tablet | Amount | % DV |
|---|---|---|
| Magnesium (as magnesium bis-glycinate) | 100 mg | 24% |
Other Ingredients: Microcrystalline cellulose, stearic acid (vegetable), croscarmellose sodium, silica.
Free from: Gluten. Dairy. GMOs (verified). Artificial colors and flavors.
Warnings (worth reading)
- Consult your doctor before use if you have kidney disease or impaired kidney function, since magnesium is cleared by the kidneys and can build up to unsafe levels if that function is reduced.
- Consult your doctor or pharmacist before use if you take antibiotics (tetracycline or quinolone-class), bisphosphonate medication, or blood pressure medication, since magnesium can interact with each of these.
- If combining with another magnesium supplement, account for your total elemental magnesium intake.
- Consult your doctor before use if you are pregnant or nursing.
- Discontinue and consult a physician if you experience adverse effects.
- Keep out of reach of children. Store in a cool, dry place.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. It is not a substitute for professional medical advice. For anything you are unsure about, talk to a qualified healthcare provider.
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